Course overview
This course is to introduce the principles of bioprocess engineering focusing on downstream bioprocessing. It aims to provide the latest bioprocess technology from an engineering point of view, using worked examples related to biological systems. This course introduces the commonly used technologies for biological products. The covered topics include centrifugation, filtration, precipitation, membrane separation, adsorption chromatography, size exclusion chromatography, liquid-liquid separation. The basic principles and mechanism of separation are covered in each of the topics, wherein the engineering concept and integrated process design are emphasized.
Course learning outcomes
- Gain in depth understanding of different unit operations in downstream processing
- Understand principles of process development and scale-up of chromatography
- Calculations and design different unit operations in downstream processing
- Recieve practical training on preparative chromatographic separation
- Understand emerging trends and future directions in downstream processing