Course overview
The aim of this course is to assist students to understand the principles of disease processes and underlying common pathological conditions that are relevant to medical radiation science. Introduction to pathology, concepts of disease, aetiology, pathogenesis and reaction to disease. Stress, cell injury, adaptation: atrophy, hypertrophy, hyperplasia, metaplasia, dysplasia. Cell death and necrosis, reversible and irreversible injury. Inflammatory process, immune alterations, infectious processes. Acid-base and electrolyte imbalances. Host-parasite relationship, manifestations of infectious disease. Neoplasia: benign and malignant neoplasm, carcinogenesis, angiogenesis, metastasis, clinical aspects. Understanding of the pathological basis of systems including: haemopoietic, cardiovascular, respiratory, renal, digestive, nervous, skeletal, endocrine, reproductive system.
Course learning outcomes
- Develop a basic understanding of the pathological basis of disease & characterise the disease process in terms of etiology, pathogenesis, morphology, clinical manifestations and prognosis
- Understand of the general concepts of stress, adaptations of cells, organs, injury, inflammation/infection and cellular repair
- Understand immune disorders
- Understand acid base/fluid electrolyte imbalance
- Appreciate the role of microbes in the pathogenesis of infectious disease
- Identify the characteristics of benign and malignant tumours
- Relate the underlying pathology of body systems (haemopoietic, cardiovascular, respiratory, renal, digestive, nervous, skeletal, endocrine, reproductive system) to their clinical manifestations