Course overview
Theoretical aspects and applications of a variety of synthetically useful reactions are presented. The course continually expands the arsenal of powerful synthetic methods available and exemplifies their uses. It focuses on efficiency (how is the greatest amount of the desired compound obtained in the fewest steps?), chemo- and regio-selectivity (how is the desired reaction obtained only at the site of interest?) and stereochemistry (how are the absolute and relative stereochemistry of the products of various reactions controlled?). An overview is given of synthetic strategy including the design and control of stereochemistry in the synthesis of complex molecules. The applications of chemical principles in a variety of contexts including industrial processes and chiral synthesis are addressed.
Course learning outcomes
- Describe and explain the use of the carbonyl group, stereoselectivity, and organometallic reagents and catalysts in chemical synthesis.
- propose mechanisms for chemical reactions, given starting materials, reagents, conditions, and/or products.
- explain the role and relevance of organic synthesis and organometallic reagents and catalysts in industrial processes.
- demonstrate proficiency in undertaking individual and/or team-based laboratory investigations using appropriate apparatus and safe laboratory practices, including the collection, analysis, interpretation and communication of results of an experiment.
- design and plan an investigation by selecting and applying appropriate practical and/or theoretical techniques or tools.