Course overview
This is an advanced course that includes a detailed examination of the cellular and molecular biology of the immune system, immune responses to microbial pathogens and other antigenic stimuli and immunisation against infections in humans and animals. Topics to be covered include: differentiation and activation of leukocytes; functions of leukocyte subsets; cell biology of antigen processing and presentation; molecular recognition of antigen; molecular and cellular bases of inflammation; signal transduction in immune cells; characteristics and functions of cytokines; mechanisms of immunoregulation; cellular communication and leukocyte traffic through tissues; production and use of monoclonal antibodies; local immunity at mucosal surfaces; immunity to infectious agents, including bacteria, viruses and parasites; inflammatory and autoimmune diseases such as asthma and arthritis; control and prevention of infections; strategies for the design and use of vaccines and gene therapy; important diseases will be considered as specific examples.
Course learning outcomes
- Understanding of the molecular and cellular mechanisms that underpin the pathogenesis and control of infections, and the interaction of pathogens with the immune system
- Developed organisational and time management skills and the capacity for multi-tasking
- Developed the ability to work in small teams and to communicate and coordinate outcomes with a larger group of colleagues