Course overview
The aim of this course is to provide an understanding of classical and current genetic principles, techniques, and their application.
Mendelian inheritance, independent assortment and mapping of genes, gene interaction, gene isolation and manipulation, the genetics of bacteria and their viruses, regulation of gene expression, epigenetics, DNA mutation, recombination and repair, genomics and proteomics, evolution and the inheritance of complex traits.
Course learning outcomes
- Describe the principles of Mendelian inheritance and the molecular basis for inheritance of traits and the impact of genetic variation on phenotype.
- Apply classical and modern genetic principles to the analysis of progeny and population phenotype to explain the basis for inheritance of traits.
- Design experiments to test for interactions between genes and infer the interaction of genes in pathways based on experimental evidence.
- Employ appropriate statistical tests to test the validity of genetic hypotheses.
- Apply laboratory genetic techniques to address questions of genetic interactions and the effects of genetic variation on phenotype.
- Integrate principles of classical and molecular genetics to develop an understanding of the genetic mechanisms of human inherited disease, the inheritance of complex traits, and evolution.