Course overview
This advanced course examines the molecular basis of host-pathogen interactions for bacterial, viral and parasite infections of significant global and medical importance. This includes how these interactions contribute to the pathogenesis (i.e. mechanisms of disease) and subsequent transmission of the pathogens to new hosts, their dependence on access to nutrients and evasion of host clearance mechanisms. Key strategies used by pathogens to survive in the host, along with the importance of vaccines, antimicrobial drugs, the microbiome and tools used to research and identify pathogens will also be discussed. The lecture program is complemented by tutorials, which extend skills in exploring and critically assessing the scientific literature, and practicals which develop advanced experimental skills for the study of pathogenic mechanisms.
Course learning outcomes
- To gain an understanding of the molecular mechanisms that underpin the pathogenesis and control of bacterial, virus, and parasite infections, and the interaction of microbial pathogens with the immune system.
- To gain a body of experimental skills and techniques frequently used in molecular microbiology research which are fundamental to understanding how research in these disciplines is conducted.
- To develop essential skills in experimental design, techniques and execution which are highly relevant to solving problem in microbial pathogenesis and many other areas of scientific research.
- To develop organisational and time management skills and the capacity for multi-tasking.
- To foster the ability to work in small teams and to communicate and coordinate outcomes with a larger group of colleagues.
- To become exposed to experimental processes that develop over many weeks, building up a framework of experience with techniques and concepts that could not readily be obtained in the course of a semester within a single research laboratory.
- To be adequately educated and mentored through close contact with academic staff.